Naltrexone Hydrochloride
Pharmaceutical-grade Naltrexone Hydrochloride (CAS 16676-29-2), 98–102%, supplied wholesale by Zyntex to licensed producers. Long-acting opioid antagonist API for tablets and extended-release injectables. CoA and SDS with every lot.
Description
Naltrexone Hydrochloride Product Overview
Naltrexone hydrochloride (C20H23NO4·HCl) is a white to off-white crystalline powder that is soluble in water. The free base (CAS 16590-41-3) is used for some extended-release products.
Pharmaceutical companies use the hydrochloride in film-coated tablets for addiction medicine, while the base is used in extended-release injectable microspheres given once a month. Low-dose formulations are also studied for other uses. Compared with the short-acting Naloxone hydrochloride 2-hydrate, it acts much longer and is used for maintenance rather than emergencies.
Like naloxone, naltrexone is produced from controlled opioid starting materials but is itself not controlled in most countries. Zyntex supplies it only to licensed pharmaceutical companies.
Key Applications of Naltrexone Hydrochloride
Main application areas:
💊 Tablets
API for film-coated tablets.
💉 Extended-Release Injectables
Base form for monthly microsphere injections.
🔬 Research
Material for low-dose formulation research.
🔬 Generic Development
Development and reference material.
Naltrexone Hydrochloride Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Naltrexone Hydrochloride |
| CAS Number | 16676-29-2 (base: 16590-41-3) |
| Assay / Purity (HPLC) | 98.0% – 102.0% (On Dried Basis) |
| Appearance | White to off-white crystalline powder |
| Specific Optical Rotation | -187° to -197° |
| Loss on Drying | ≤ 1.0% |
| Documents | CoA and SDS with every lot |
⚠️ Safety & Handling: Pharmacologically active substance; harmful if swallowed. Avoid inhalation of dust and contact with skin and eyes; wear gloves, eye protection and dust protection. Store in tightly closed, light-resistant containers in a cool, dry place. Always consult the Safety Data Sheet (SDS) for full classification and handling instructions.
Frequently Asked Questions
Do you supply naltrexone base for injectables?
The free base used in extended-release injectables can be quoted on request, in addition to the hydrochloride.
Is naltrexone a controlled substance?
In most countries it is not, but it is produced from controlled starting materials. Buyers must check local regulations.
How can I get a price and documents?
Prices depend on quantity, packaging and destination. Contact us with your required volume to receive a quotation together with the CoA and SDS.
