Naloxone Hydrochloride 2-Hydrate
Pharmaceutical-grade Naloxone Hydrochloride Dihydrate (CAS 51481-60-8), 98–102%, supplied wholesale by Zyntex to licensed producers. Opioid antagonist API for overdose nasal sprays, injections and combination tablets. CoA and SDS.
Description
Naloxone Hydrochloride Dihydrate Product Overview
Naloxone hydrochloride dihydrate (C19H21NO4·HCl·2H2O) is a white to off-white crystalline powder that is soluble in water. It blocks opioid receptors and rapidly reverses the effects of opioids.
Pharmaceutical companies use it in injections and nasal sprays for emergency treatment of opioid overdose; it is on the WHO Model List of Essential Medicines, and in many countries nasal sprays are available without prescription. It is also combined with opioids in some tablets to deter misuse. A related, longer-acting antagonist in our range is Naltrexone hydrochloride.
Naloxone itself is not a controlled substance in most countries, but it is derived from controlled opioid starting materials. Zyntex supplies it only to licensed pharmaceutical companies.
Key Applications of Naloxone Hydrochloride Dihydrate
Main application areas:
👃 Nasal Sprays
API for emergency overdose nasal sprays.
💉 Injections
API for injectable formulations.
💊 Combination Tablets
API in abuse-deterrent combinations.
🔬 Generic Development
Development and reference material.
Naloxone Hydrochloride Dihydrate Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Naloxone hydrochloride 2-hydrate |
| CAS Number | 51481-60-8 |
| Molecular Formula | C19H21NO4·HCl·2H2O |
| Assay (HPLC) | 98.0% – 102.0% (Anhydrous) |
| Appearance | White to off-white crystalline powder |
| Documents | CoA and SDS with every lot |
⚠️ Safety & Handling: Pharmacologically active substance; harmful if swallowed. Avoid inhalation of dust and contact with skin and eyes; wear gloves, eye protection and dust protection. Store in tightly closed, light-resistant containers in a cool, dry place. Always consult the Safety Data Sheet (SDS) for full classification and handling instructions.
Frequently Asked Questions
Is it a controlled substance?
In most countries it is not, but it is made from controlled opioid starting materials. Buyers must check local regulations.
What is the difference between naloxone and naltrexone?
Both block opioid receptors. Naloxone acts quickly and briefly for emergencies, while naltrexone acts longer and is used for maintenance.
How can I get a price and documents?
Prices depend on quantity, packaging and destination. Contact us with your required volume to receive a quotation together with the CoA and SDS.
