Levodopa
Pharmaceutical-grade Levodopa (L-DOPA, CAS 59-92-7), 99.0–101.0%, supplied wholesale by Zyntex to licensed producers. Dopamine precursor API for combination tablets, controlled-release products and intestinal gels. CoA and SDS.
Description
Levodopa Product Overview
Levodopa (C9H11NO4) is a white or almost white crystalline powder that is slightly soluble in water and freely soluble in dilute hydrochloric acid. It is the L-enantiomer of DOPA, and its optical purity is controlled by specific rotation.
Pharmaceutical companies use it in medicines for Parkinson’s disease, almost always combined with a peripheral decarboxylase inhibitor such as Benserazide hydrochloride or Carbidopa. These combinations are formulated as tablets, dispersible tablets, controlled-release tablets, capsules and intestinal gels. Related APIs in this field include Biperiden Hydrochloride.
Levodopa oxidizes easily and darkens in light and air, so it must be protected during storage and processing. Zyntex supplies it only to licensed pharmaceutical companies.
Key Applications of Levodopa
Main application areas:
💊 Combination Tablets
Combined with benserazide or carbidopa.
⏱️ Controlled Release
API for modified-release tablets and capsules.
💧 Intestinal Gels
API for continuous delivery products.
🔬 Generic Development
Development and reference material.
Levodopa Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Levodopa (L-DOPA) |
| CAS Number | 59-92-7 |
| Molecular Formula / Weight | C9H11NO4 / 197.19 g/mol |
| Assay / Purity (HPLC) | 99.0% to 101.0% (Dry Basis) |
| Appearance | White or almost white crystalline powder |
| Specific Rotation | -160° to -167° |
| Solubility | Slightly soluble in water; practically insoluble in ethanol; freely soluble in dilute HCl |
| Documents | CoA and SDS with every lot |
⚠️ Safety & Handling: Pharmacologically active substance; avoid inhalation of dust and contact with skin and eyes. Wear gloves, eye protection and dust protection. Store in tightly closed, light-resistant containers in a cool, dry place, as the substance oxidizes and darkens in light and air. Always consult the Safety Data Sheet (SDS) for full classification and handling instructions.
Frequently Asked Questions
Why is it combined with benserazide or carbidopa?
These decarboxylase inhibitors prevent levodopa from being converted to dopamine outside the brain, so more reaches its target and side effects are reduced.
Who can purchase this API?
It is supplied only to pharmaceutical companies holding the licenses required for API purchase and use in their country.
How can I get a price and documents?
Prices depend on quantity, packaging and destination. Contact us with your required volume to receive a quotation together with the CoA and SDS.
