Amlodipine Besylate
USP/EP-grade Amlodipine Besylate (CAS 111470-99-6), 97–102%, supplied wholesale by Zyntex to licensed producers. Dihydropyridine calcium channel blocker API for tablets and fixed-dose combinations. CoA and SDS with every lot.
Description
Amlodipine Besylate Product Overview
Amlodipine besylate is the benzenesulfonate salt of amlodipine. It is a white or almost white powder that is slightly soluble in water. Developers chose the besylate salt because it is more stable and less hygroscopic than other salts, which simplifies tablet production. An alternative salt form, Amlodipine maleate, is also available.
Pharmaceutical companies use it in tablets in the calcium channel blocker class, alone and in many fixed-dose combinations, for example with Valsartan, losartan or Atorvastatin Calcium. It belongs to the same dihydropyridine family as Nifedipine, but its long half-life allows once-daily dosing.
Amlodipine is light-sensitive, so producers protect it during storage and processing. Zyntex supplies it from qualified API producers with lot-specific documentation, only to licensed pharmaceutical companies.
Key Applications of Amlodipine Besylate
Main application areas:
💊 Tablets
API for once-daily calcium channel blocker tablets.
🔗 Fixed-Dose Combinations
Combined with ARBs, statins and other APIs.
🔬 Generic Development
Development and reference material.
🧪 Analytical Use
Reference material for quality control.
Amlodipine Besylate Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Amlodipine besylate |
| CAS Number | 111470-99-6 |
| Molecular Formula / Weight | C20H25ClN2O5·C6H6O3S / 567.05 g/mol |
| Grade | Pharmaceutical Grade (USP/EP) |
| Assay | 97.0% – 102.0% (Anhydrous Basis) |
| Category | Calcium Channel Blockers & Cardiovascular API |
| Documents | CoA and SDS with every lot |
⚠️ Safety & Handling: Potent pharmacologically active substance, harmful if swallowed. Avoid inhalation of dust and contact with skin and eyes; wear gloves, eye protection and dust protection. Store in tightly closed, light-resistant containers in a cool, dry place. Always consult the Safety Data Sheet (SDS) for full classification and handling instructions.
Frequently Asked Questions
Why is the besylate salt preferred?
The besylate salt offers good stability and low hygroscopicity, which makes tablet production more robust than with some other salts.
Do you also supply amlodipine maleate?
Yes. Amlodipine maleate is available as a separate product for formulations that require that salt.
How can I get a price and documents?
Prices depend on quantity, packaging and destination. Contact us with your required volume to receive a quotation together with the CoA and SDS.
