Methyl Cyanoacetate
Methyl Cyanoacetate (CAS 105-34-0), min. 99%, supplied wholesale by Zyntex. Active methylene building block for pharmaceutical intermediates, dyes, agrochemicals and cyanoacrylate adhesives. CoA and SDS with every lot.
Description
Methyl Cyanoacetate Product Overview
Methyl cyanoacetate (C4H5NO2) is a clear, colorless to pale yellow liquid that boils at about 202–205°C. Its molecule contains a nitrile group and an ester group on either side of one CH2 group. This so-called active methylene group reacts easily, which makes the compound a versatile building block.
Chemists use it in Knoevenagel condensations with aldehydes such as Benzaldehyde, in alkylations and in the construction of heterocycles such as pyrimidines, pyridines and pyrazoles. These routes lead to pharmaceutical intermediates, vitamins, dyes and pigments, and agrochemicals. Methyl cyanoacrylate, the monomer of fast-setting instant adhesives, is also made from it.
The ethyl ester, Ethyl Cyanoacetate, works in a similar way and is often used as an alternative, depending on the target molecule and process. In heterocycle chemistry, it is sometimes combined with Urea or related nitrogen reagents.
Key Applications of Methyl Cyanoacetate
Main application areas:
💊 Pharmaceutical Intermediates
Building block for heterocyclic API intermediates.
🎨 Dyes and Pigments
Intermediate for methine and azo dyes.
🌱 Agrochemicals
Starting material for crop protection intermediates.
🧪 Adhesives
Raw material for methyl cyanoacrylate monomer.
Methyl Cyanoacetate Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Methyl cyanoacetate |
| CAS Number | 105-34-0 |
| EC Number | 203-288-0 |
| Molecular Formula / Weight | C4H5NO2 / 99.09 g/mol |
| Assay (Purity) | Min. 99% |
| Boiling Point | ~202°C |
| Documents | CoA and SDS with every lot |
⚠️ Safety & Handling: Harmful if swallowed and causes serious eye irritation. Avoid contact with skin and eyes and inhalation of vapors, and wear chemical-resistant gloves and eye protection. Store in tightly closed containers in a cool, ventilated place, away from strong acids, bases and oxidizers. Always consult the Safety Data Sheet (SDS) for full classification and handling instructions.
Frequently Asked Questions
What is the difference between methyl and ethyl cyanoacetate?
Both are active methylene building blocks with very similar chemistry. The choice depends on the target molecule, the ester group needed and process conditions.
Which purity do you supply?
Minimum 99% purity, suitable for pharmaceutical and fine chemical synthesis. Lot-specific values are given on the CoA.
How can I get a price and documents?
Prices depend on quantity, packaging and destination. Contact us with your required volume to receive a quotation together with the CoA and SDS.
