Gemcitabine Hydrochloride
Pharmaceutical-grade Gemcitabine Hydrochloride (CAS 122111-03-9), 98–102%, supplied wholesale by Zyntex to licensed producers. Cytotoxic nucleoside analogue API for lyophilized and ready-to-use oncology infusions. CoA and SDS.
Description
Gemcitabine Hydrochloride Product Overview
Gemcitabine hydrochloride (C9H11F2N3O4·HCl) is a white to off-white crystalline powder that is soluble in water. It is a difluorinated analogue of deoxycytidine that interferes with DNA synthesis in dividing cells.
Pharmaceutical companies use it in lyophilized powders and ready-to-use solutions for intravenous infusion in oncology, often in combination with other cytotoxic agents. Related antimetabolite APIs in our range include Fluorouracil and the purine analogue Azathioprine.
As a cytotoxic API, gemcitabine must be handled in dedicated, contained facilities, and injectable products require sterile processing with endotoxin control. Zyntex supplies it only to licensed pharmaceutical companies with appropriate capabilities.
Key Applications of Gemcitabine Hydrochloride
Main application areas:
💉 Infusion Products
API for lyophilized and ready-to-use infusions.
🏥 Oncology
Cytotoxic API for combination regimens.
🔬 Generic Development
Development and reference material.
🧪 Analytical Use
Reference material for impurity methods.
Gemcitabine Hydrochloride Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Gemcitabine Hydrochloride |
| CAS Number | 122111-03-9 |
| Molecular Formula / Weight | C9H11F2N3O4·HCl / 299.66 g/mol |
| Assay / Purity (HPLC) | 98.0% to 102.0% (Dry Basis) |
| Appearance | White to off-white crystalline powder |
| Specific Rotation | +48.0° to +54.0° |
| Solubility | Soluble in water; slightly soluble in methanol; insoluble in ethanol |
| Documents | CoA and SDS with every lot |
⚠️ Safety & Handling: Cytotoxic substance that may cause genetic defects and damage fertility or the unborn child. Handle only in contained systems with full protective equipment and respiratory protection, following procedures for hazardous drugs. Store locked, in tightly closed containers in a cool, dry place. Always consult the Safety Data Sheet (SDS) for full classification and handling instructions.
Frequently Asked Questions
What facilities are needed to handle gemcitabine?
As a cytotoxic API, it must be processed in dedicated, contained facilities with procedures for hazardous drugs.
Who can purchase this API?
It is supplied only to licensed pharmaceutical companies with appropriate oncology production capabilities.
How can I get a price and documents?
Prices depend on quantity, packaging and destination. Contact us with your required volume to receive a quotation together with the CoA and SDS.
