Azathioprine
Pharmaceutical-grade Azathioprine (CAS 446-86-6) supplied wholesale by Zyntex to licensed producers. Purine-analogue immunosuppressant API for tablets and injectables, requiring contained handling. CoA and SDS with every lot.
Description
Azathioprine Product Overview
Azathioprine (C9H7N7O2S) is a pale yellow powder that is practically insoluble in water and ethanol and dissolves in dilute alkali. In the body, it converts to 6-mercaptopurine, which explains its activity. It is described in the USP, EP and BP.
Pharmaceutical companies use it in tablets and, as the sodium salt, in injectables in the immunosuppressant class. Because it is a potent cytotoxic substance, it requires contained handling during production. Its metabolism involves the enzyme xanthine oxidase, which links it to another purine-related API, Allopurinol.
Other antimetabolite APIs in our range include Fluorouracil and Gemcitabine Hydrochloride. Zyntex supplies it from qualified API producers with lot-specific documentation, only to licensed pharmaceutical companies.
Key Applications of Azathioprine
Main application areas:
💊 Tablets
API for immunosuppressant tablets.
💉 Injectables
Sodium salt for injectable formulations.
🔬 Generic Development
Development and reference material.
🧪 Analytical Use
Reference material for impurity testing.
Azathioprine Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Azathioprine |
| CAS Number | 446-86-6 |
| Molecular Formula / Weight | C9H7N7O2S / 277.26 g/mol |
| Appearance | Pale yellow powder |
| Assay / Purity | 98.5% – 101.0% (Pharma Grade) |
| Documents | CoA and SDS with every lot |
⚠️ Safety & Handling: Potent cytotoxic substance: may cause cancer and genetic defects and may damage fertility or the unborn child. Handle only in contained systems with suitable respiratory protection, gloves and protective clothing. Store locked, in tightly closed, light-resistant containers in a cool, dry place. Always consult the Safety Data Sheet (SDS) for full classification and handling instructions.
Frequently Asked Questions
Why does azathioprine require contained handling?
It is a potent cytotoxic and carcinogenic substance, so dust exposure must be minimized with closed systems and personal protective equipment.
Who can purchase this API?
It is supplied only to pharmaceutical companies holding the licenses required for API purchase and use in their country.
How can I get a price and documents?
Prices depend on quantity, packaging and destination. Contact us with your required volume to receive a quotation together with the CoA and SDS.
