Dabigatran

Dabigatran is a potent, reversible, and selective direct thrombin inhibitor (DTI). It is primarily used to prevent stroke and systemic embolism in patients with non-valvular atrial fibrillation.

SKU: 211915-06-9 Category: Tag:
Description
Dabigatran is, furthermore, a premier pharmaceutical Active Pharmaceutical Ingredient (API) supplied by Zyntex for the cardiovascular, clinical, and life sciences research sectors. This white to off-white solid (CAS 211915-06-9) is distinguished by being a potent, competitive, and reversible direct thrombin inhibitor. In addition, it possesses a high degree of selectivity for thrombin, the central enzyme in the coagulation cascade. Therefore, it is extensively utilized as a primary therapeutic agent for the prevention of stroke and systemic embolism in patients with atrial fibrillation and as a high-potential material for advanced anticoagulant research.

Comprehensive Product Overview

In the field of thrombosis management, the ability to directly inhibit both free and clot-bound thrombin is a major advantage. Dabigatran is specifically selected because it prevents the conversion of fibrinogen to fibrin during the clotting process. For instance, it offers a more predictable pharmacokinetic profile compared to traditional vitamin K antagonists. Consequently, it facilitates treatment without the need for routine international normalized ratio (INR) monitoring. As a result, Zyntex ensures that our high-purity Dabigatran is synthesized under strict quality controls to ensure maximum molecular efficacy.

Moreover, the pharmaceutical-grade Dabigatran provided by Zyntex is a vital component in the development of oral prodrug formulations (such as Dabigatran Etexilate). This application allows for the creation of high-bioavailability cardiovascular therapies, undoubtedly pushing the boundaries of what is possible in preventive medicine. At the same time, its role in the treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE) is highly valued by global pharmaceutical firms. In short, our product serves as a dependable “precision-reagent” for companies focusing on both chronic anticoagulation and sustainable healthcare infrastructure.

Recently, scientific interest has surged regarding the use of Dabigatran in clinical studies involving post-surgical venous thromboembolism prevention. Because of this, Zyntex offers specialized analytical documentation and high-purity batches to provide reliable outcomes in laboratory environments. Ultimately, by choosing Zyntex as your supplier, you secure a reliable supply chain that balances therapeutic potency with rigorous logistical safety. To conclude, our commitment to chemical excellence ensures that your manufacturing processes—whether in fine chemistry or clinical research—achieve the highest levels of purity and chemical yield.

Key Industrial Applications

This high-potency direct thrombin inhibitor is specifically vital in the following four sectors:

🧪 Cardiovascular Research

A potent agent for thrombin inhibition; thus enabling the production of high-value anticoagulant research models.

💊 Pharmaceutical Formulation

Key material for prodrug development; consequently vital for the next generation of oral anticoagulants.

🔬 Clinical Bioassays

Used as a reference standard in coagulation assays; undoubtedly essential for advanced diagnostic technologies.

⚗️ Specialty Synthesis

Used in the synthesis of complex benzimidazole derivatives; specifically helping to control molecular structural integrity.

Technical Specifications

ParameterStandard Value
Product NameDabigatran
Assay / PurityMin. 98.0% – 99.0%
Molecular FormulaC25H25N7O3
CAS Number211915-06-9

⚠️ Safety Warning: Dabigatran is a potent anticoagulant. Therefore, it must be handled by trained professionals in laboratory settings. Exposure can lead to increased bleeding risk; it must be stored in a cool, dry place away from incompatible oxidizing agents.