Warfarin sodium
Zyntex provides high-purity Warfarin Sodium. As a leading vitamin K antagonist, this API is essential for the prevention and treatment of thrombosis and embolism, offering reliable oral anticoagulation therapy.
Description
Comprehensive Product Overview
In clinical cardiovascular therapy, Warfarin Sodium remains a foundational treatment despite the emergence of newer agents. Its primary mechanism of action involves the inhibition of the vitamin K epoxide reductase (VKORC1) enzyme. First, this inhibition prevents the recycling of vitamin K, which is essential for the gamma-carboxylation of clotting factors II, VII, IX, and X. As a result, the synthesis of these biologically active coagulation factors is suppressed, effectively lengthening the blood clotting time. Zyntex provides Warfarin Sodium with rigorous batch-to-batch consistency, which is vital given the drug’s narrow therapeutic index and the need for precise INR (International Normalized Ratio) monitoring.
Zyntex ensures that our Warfarin Sodium meets the highest standards for impurity profiles and crystalline uniformity. Because Warfarin is highly potent, even minor variations in the API can lead to significant clinical consequences. Our product is designed for optimal compression characteristics in tablet manufacturing, ensuring content uniformity across all dosage strengths. Moreover, we provide comprehensive documentation regarding the salt’s moisture sensitivity and light stability. Consequently, our product helps manufacturers deliver a reliable, life-saving therapy that healthcare providers have trusted for decades. Finally, our commitment to regulatory compliance ensures that your finished formulations can move smoothly through global approval processes.
Key Pharmaceutical Applications
This essential anticoagulant API is the cornerstone of several life-saving therapies:
🧠 Stroke Prevention
The standard of care for patients with atrial fibrillation (AFib) to prevent the formation of blood clots that can lead to ischemic stroke.
🦵 VTE & PE Treatment
Critical for treating Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE), preventing clot expansion and recurrence.
❤️ Artificial Valve Management
Indispensable for patients with mechanical heart valves to prevent valve thrombosis and related systemic embolism.
🔬 Coagulation Research
Used as a reference standard in hematology labs for calibrating coagulation assays and studying vitamin K metabolism.
Technical Specifications
| Parameter | Specification Standard |
|---|---|
| Product Name | Warfarin Sodium |
| CAS Number | 129-06-6 |
| Molecular Formula | C19H15NaO4 |
| Assay (HPLC) | 98.0% – 102.0% (USP Standard) |
| Appearance | White, crystalline powder |
🔬 Scientific Data: For detailed pharmacokinetics and metabolic pathway information, consult: PubChem Entry: Warfarin Sodium (External Link)
