Crospovidone
USP/NF and EP-grade Crospovidone (cross-linked PVP, CAS 25249-54-1), standard and fine grades, supplied wholesale by Zyntex. Superdisintegrant for tablets, ODTs and capsules, and beverage clarification. CoA and SDS.
Description
Crospovidone Product Overview
Crospovidone is a white to creamy-white, free-flowing powder that is insoluble in water. Unlike Povidone (PVP K30), it is cross-linked, so it swells and wicks water rapidly without forming a gel, which breaks tablets apart quickly.
In addition, pharmaceutical and nutritional producers use it at about 2–5% as a disintegrant in tablets made by direct compression or granulation, and in orally disintegrating tablets. Similarly, beverage producers use special grades to remove polyphenols from beer and wine. Fine grades suit small tablets and ODTs, whereas coarse grades act fastest in larger tablets.
Notably, related excipients in our range include Croscarmellose Sodium, Sodium Starch Glycolate and Microcrystalline Cellulose (MCC).
Key Applications of Crospovidone
Typical uses include, for example:
💊 Tablets
Superdisintegrant at 2–5%.
👅 ODTs
Fast-disintegrating tablets.
💊 Capsules
Disintegration aid.
🍺 Beverage Clarification
Polyphenol removal grades.
Crospovidone Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Crospovidone (Cross-linked PVP) |
| CAS Number | 25249-54-1 |
| Grade | USP/NF, EP |
| Types | Standard (coarse) and fine particle |
| Appearance | White to creamy-white powder |
| Documents | CoA and SDS with every lot |
⚠️ Safety & Handling: Not classified as hazardous under GHS; fine dust may form explosive mixtures with air. Avoid dust formation. Store in tightly closed containers in a dry place. Always consult the Safety Data Sheet (SDS), because it contains the full classification and handling instructions.
Frequently Asked Questions
How does crospovidone differ from povidone?
It is cross-linked and insoluble, so it acts as a disintegrant rather than a binder.
How does it compare with croscarmellose?
Both are superdisintegrants; crospovidone swells without gelling and suits ODTs well.
How can I get a price and documents?
We supply flexible quantities, from small orders to large volumes, so you do not need to meet the high minimum orders of large producers. Please contact us with your required volume, and we will send a quotation together with the CoA and SDS.
