Croscarmellose Sodium

USP/NF and EP-grade Croscarmellose Sodium (CAS 74811-65-7) supplied wholesale by Zyntex. Superdisintegrant for tablets, capsules and orally disintegrating tablets. CoA and SDS with every lot.

SKU: 74811-65-7 Category: Tag:
Description
Croscarmellose Sodium (CAS 74811-65-7) is a cross-linked sodium carboxymethyl cellulose used as a superdisintegrant in tablets and capsules. Zyntex is a wholesale supplier and distributor of USP/NF and EP-grade Croscarmellose Sodium in flexible quantities, with a CoA as well as an SDS for every lot.

Croscarmellose Sodium Product Overview

Croscarmellose sodium is a white to off-white, free-flowing powder that is insoluble in water but swells rapidly to several times its volume when wet. This swelling breaks tablets apart quickly, which speeds up dissolution of the active ingredient.

In addition, pharmaceutical companies use it at about 0.5–5% in tablets made by direct compression or wet granulation, and in capsules and orally disintegrating tablets. Similarly, producers of nutritional tablets use it to meet disintegration requirements. It works well together with fillers such as Microcrystalline Cellulose (MCC) and Lactose Monohydrate and with lubricants such as Magnesium Stearate.

Because generic tablet producers need it in very different volumes, Zyntex supplies flexible quantities without high minimum orders. Related disintegrants in our range include Sodium Starch Glycolate.

Key Applications of Croscarmellose Sodium

Typical uses include, for example:

💊 Tablets

Superdisintegrant at 0.5–5%.

💊 Capsules

Faster capsule disintegration.

👅 ODTs

Orally disintegrating tablets.

🥤 Nutritional Tablets

Disintegration of vitamin tablets.

Croscarmellose Sodium Technical Specifications

ParameterStandard Value
Product NameCroscarmellose Sodium
CAS Number74811-65-7
GradeUSP/NF, EP
AppearanceWhite to off-white powder
Typical Use Level0.5% – 5% in tablets
DocumentsCoA and SDS with every lot

⚠️ Safety & Handling: Not classified as hazardous under GHS; fine dust may form explosive mixtures with air. Avoid dust formation and also wear dust protection. Store in tightly closed containers in a dry place. Always consult the Safety Data Sheet (SDS), because it contains the full classification and handling instructions.

Frequently Asked Questions

How does croscarmellose sodium work?

It swells rapidly in water and breaks the tablet apart, so the active ingredient dissolves faster.

How does it compare with sodium starch glycolate?

Both are superdisintegrants; the choice depends on the formulation, and some producers use them together.

How can I get a price and documents?

We supply flexible quantities, from small orders to large volumes, so you do not need to meet the high minimum orders of large producers. Please contact us with your required volume, and we will send a quotation together with the CoA and SDS.