Carbidopa

Pharmaceutical-grade Carbidopa monohydrate (CAS 28860-95-9), 98.5–101%, supplied wholesale by Zyntex to licensed producers. Decarboxylase inhibitor API for levodopa combination tablets, extended-release products and gels. CoA and SDS.

SKU: 28860-95-9 Category: Tag:
Description
Carbidopa (carbidopa monohydrate, CAS 28860-95-9) is a peripheral decarboxylase inhibitor supplied as an active pharmaceutical ingredient (API) for levodopa combination products. Zyntex is a wholesale supplier and distributor of pharmaceutical-grade Carbidopa to licensed producers, with a CoA as well as an SDS for every lot.

Carbidopa Product Overview

Carbidopa monohydrate (C10H14N2O4·H2O) is a white to off-white crystalline powder that is slightly soluble in water. It is the (S)-enantiomer, so chiral purity remains controlled.

In addition, pharmaceutical companies combine it with Levodopa in immediate-release and controlled-release tablets, orally disintegrating tablets, extended-release capsules and intestinal gels for Parkinson’s disease. In this role, it blocks the conversion of levodopa outside the brain, similarly to Benserazide hydrochloride, which appears in other combinations.

Because hydrazine is a potential impurity, specifications limit it tightly. Zyntex therefore supplies it from qualified API producers, only to licensed pharmaceutical companies.

Key Applications of Carbidopa

Typical uses include, for example:

💊 Combination Tablets

Combined with levodopa in tablets.

⏱️ Controlled Release

API for extended-release products.

💧 Intestinal Gels

API for continuous delivery products.

🔬 Generic Development

Development as well as reference material.

Carbidopa Technical Specifications

ParameterStandard Value
Product NameCarbidopa Monohydrate
CAS Number28860-95-9
Molecular FormulaC10H14N2O4·H2O
Assay / Purity98.5% – 101.0%
AppearanceWhite to off-white crystalline powder
DocumentsCoA as well as SDS with every lot

⚠️ Safety & Handling: Pharmacologically active substance; avoid inhalation of dust and contact with skin and eyes. Wear gloves, eye protection and dust protection. Store in tightly closed, light-resistant containers in a cool, dry place, so that the material stays in good condition. Always consult the Safety Data Sheet (SDS), because it contains the full classification and handling instructions.

Frequently Asked Questions

What is the difference between carbidopa and benserazide?

Both block levodopa conversion outside the brain; they simply appear in different combination products depending on the market.

Why is hydrazine controlled in carbidopa?

Because hydrazine is a potential impurity of concern, pharmacopoeias set strict limits for it.

How can I get a price and documents?

Prices depend on quantity, packaging and destination, so please contact us with your required volume. We then send a quotation together with the CoA and SDS.