
Pharmaceutical-grade Carbidopa monohydrate (CAS 28860-95-9), 98.5–101%, supplied wholesale by Zyntex to licensed producers. Decarboxylase inhibitor API for levodopa combination tablets, extended-release products and gels. CoA and SDS.
Carbidopa monohydrate (C10H14N2O4·H2O) is a white to off-white crystalline powder that is slightly soluble in water. It is the (S)-enantiomer, so chiral purity remains controlled.
In addition, pharmaceutical companies combine it with Levodopa in immediate-release and controlled-release tablets, orally disintegrating tablets, extended-release capsules and intestinal gels for Parkinson’s disease. In this role, it blocks the conversion of levodopa outside the brain, similarly to Benserazide hydrochloride, which appears in other combinations.
Because hydrazine is a potential impurity, specifications limit it tightly. Zyntex therefore supplies it from qualified API producers, only to licensed pharmaceutical companies.
Typical uses include, for example:
💊 Combination Tablets
Combined with levodopa in tablets.
⏱️ Controlled Release
API for extended-release products.
💧 Intestinal Gels
API for continuous delivery products.
🔬 Generic Development
Development as well as reference material.
| Parameter | Standard Value |
|---|---|
| Product Name | Carbidopa Monohydrate |
| CAS Number | 28860-95-9 |
| Molecular Formula | C10H14N2O4·H2O |
| Assay / Purity | 98.5% – 101.0% |
| Appearance | White to off-white crystalline powder |
| Documents | CoA as well as SDS with every lot |
⚠️ Safety & Handling: Pharmacologically active substance; avoid inhalation of dust and contact with skin and eyes. Wear gloves, eye protection and dust protection. Store in tightly closed, light-resistant containers in a cool, dry place, so that the material stays in good condition. Always consult the Safety Data Sheet (SDS), because it contains the full classification and handling instructions.
What is the difference between carbidopa and benserazide?
Both block levodopa conversion outside the brain; they simply appear in different combination products depending on the market.
Why is hydrazine controlled in carbidopa?
Because hydrazine is a potential impurity of concern, pharmacopoeias set strict limits for it.
How can I get a price and documents?
Prices depend on quantity, packaging and destination, so please contact us with your required volume. We then send a quotation together with the CoA and SDS.