Benserazide hydrochloride

Benserazide hydrochloride by Zyntex is a high-purity peripheral decarboxylase inhibitor (CAS 14919-77-8). It is a critical pharmaceutical active used exclusively in combination with L-Dopa to treat Parkinson’s disease, preventing the premature conversion of L-Dopa in the bloodstream and ensuring maximum delivery to the central nervous system.

SKU: 14919-77-8 Category: Tags: ,
Description
Benserazide hydrochloride is a potent peripheral aromatic L-amino acid decarboxylase (AAAD) inhibitor. Zyntex provides this premium pharmaceutical-grade crystalline powder (CAS 14919-77-8) for the global neurology, pharmaceutical manufacturing, and clinical research sectors. This compound acts by blocking the enzyme responsible for converting levodopa into dopamine outside of the brain. It effectively acts as a “protector” for levodopa, significantly increasing its bioavailability. In addition, it reduces the incidence of systemic side effects such as nausea and heart palpitations. Therefore, formulators rely on it for the production of fixed-dose combination tablets (e.g., Madopar) used in the long-term management of Parkinson’s disease.

Comprehensive Product Overview of Benserazide Hydrochloride

Exceptional enzymatic inhibition and synergistic performance provide a major advantage in neuro-pharmacology. Benserazide hydrochloride works by ensuring that levodopa remains intact until it crosses the blood-brain barrier, making it a “gold standard” in combination therapy for movement disorders. It helps clinicians achieve therapeutic dopamine levels in the brain with lower total doses of levodopa. For instance, it is a primary component in producing 4:1 ratio formulations (Levodopa/Benserazide). Consequently, it enhances both motor function recovery and patient tolerance to medication. As a result, Zyntex ensures high assay purity and strict control of related substances for our supply. This ensures maximum stability and predictable pharmacokinetic profiles in your manufacturing cycles.

Moreover, Zyntex supplies pharmaceutical-grade Benserazide hydrochloride for advanced drug delivery research. This compound acts as a critical tool in studying the metabolic pathways of catecholamines. It pushes the boundaries of neurology by enabling the development of controlled-release and rapid-dissolve formulations. At the same time, it serves as a stabilizer in complex multi-component drug systems. In short, our product serves as a dependable “bioavailability enhancer.” It supports both the rigorous clinical requirements of geriatric medicine and the innovative needs of the global pharmaceutical industry.

Recently, scientific interest in Benserazide hydrochloride for its role in preventing dopamine-induced oxidative stress in peripheral tissues has grown. It provides high efficacy in streamlining Parkinson’s treatment protocols. Because of this, Zyntex offers specialized grades with verified chemical profiles to meet international pharmacopeia standards (EP/USP). These formats suit modern pharmaceutical engineering and specialized clinical R&D. Ultimately, choosing Zyntex secures a reliable and transparent chemical supply chain. We balance amino acid derivative expertise with rigorous batch-to-batch quality monitoring. To conclude, our commitment ensures your manufacturing processes achieve the highest levels of performance and stability.

Key Industrial Applications for Benserazide Hydrochloride

This high-performance decarboxylase inhibitor is vital in these four sectors:

🧠 Anti-Parkinson’s Drugs

Essential active for fixed-dose Levodopa combinations. Thus, it provides the foundation for standard-of-care Parkinson’s therapy.

💊 Pharmaceutical R&D

Used in the development of next-generation neuro-therapeutics. Consequently, it is vital for optimizing CNS drug delivery.

🔬 Biochemical Assays

Primary reagent for enzyme inhibition studies. Undoubtedly, it is essential for analyzing decarboxylase activity in lab settings.

🏥 Specialized Medicine

Acts as a synergistic agent in the treatment of Restless Legs Syndrome (RLS). Specifically, it supports sleep quality in affected patients.

Technical Specifications

ParameterStandard Value
Product NameBenserazide Hydrochloride
Molecular Formula$C_{10}H_{16}ClN_{3}O_{5}$
Molecular Weight293.70 g/mol
CAS Number14919-77-8

⚠️ Safety & Handling: Benserazide HCl is intended for professional pharmaceutical use only. It may cause skin and eye irritation. Therefore, always handle with appropriate PPE, including gloves and a mask. It is highly sensitive to light and moisture. Store in a cool, dry, and dark environment in airtight containers to prevent degradation of the active molecule.