Paroxetine Hydrochloride
Pharmaceutical-grade Paroxetine Hydrochloride (hemihydrate CAS 110429-35-1), 98.5–102%, supplied wholesale by Zyntex to licensed producers. SSRI API for tablets, controlled-release tablets and oral suspensions. CoA and SDS.
Description
Paroxetine Hydrochloride Product Overview
Paroxetine hydrochloride is a white to off-white crystalline powder that is slightly soluble in water. The common commercial form is the hemihydrate (CAS 110429-35-1); an anhydrous form (CAS 78246-49-8) also exists. The two forms behave differently in processing, so the form must be stated in specifications.
Pharmaceutical companies use it in film-coated tablets, controlled-release tablets and oral suspensions in the SSRI class. The free base is listed separately as Paroxetine and is used mainly as a starting material for salts. Other SSRIs in our range include Sertraline Hydrochloride and Fluoxetine Hydrochloride.
Zyntex supplies paroxetine hydrochloride from qualified API producers, only to licensed pharmaceutical companies.
Key Applications of Paroxetine Hydrochloride
Main application areas:
💊 Tablets
API for film-coated tablets.
⏱️ Controlled Release
API for modified-release tablets.
🥄 Oral Suspensions
API for liquid formulations.
🔬 Generic Development
Development material in hemihydrate or anhydrous form.
Paroxetine Hydrochloride Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Paroxetine Hydrochloride |
| CAS Number | 110429-35-1 (hemihydrate) / 78246-49-8 (anhydrous) |
| Assay / Purity (HPLC) | Min 98.5% to 102.0% (Dry Basis) |
| Appearance | White to off-white crystalline powder |
| Melting Point | Approx. 120 – 138 °C (Hemihydrate form) |
| Solubility | Slightly soluble in water; freely soluble in methanol and ethanol |
| Documents | CoA and SDS with every lot |
⚠️ Safety & Handling: Pharmacologically active substance; harmful if swallowed, may damage the unborn child and is very toxic to aquatic life. Avoid inhalation of dust and contact with skin; wear gloves, eye protection and dust protection, and prevent release to the environment. Store in tightly closed containers. Always consult the Safety Data Sheet (SDS) for full classification and handling instructions.
Frequently Asked Questions
What is the difference between the hemihydrate and anhydrous forms?
They contain different amounts of water and have different crystal structures, which affects stability and processing. The hemihydrate is the most common commercial form.
Who can purchase this API?
It is supplied only to pharmaceutical companies holding the licenses required for API purchase and use in their country.
How can I get a price and documents?
Prices depend on quantity, packaging and destination. Contact us with your required volume to receive a quotation together with the CoA and SDS.
