Paroxetine

Pharmaceutical-grade Paroxetine free base (CAS 61869-08-7) supplied wholesale by Zyntex to licensed companies. Starting material for paroxetine hydrochloride and mesylate salts, formulation development and analysis. CoA and SDS.

SKU: 10101-52-7 Category: Tag:
Description
Paroxetine Base (free base, CAS 61869-08-7) is the base form of the SSRI paroxetine, supplied as a starting material for paroxetine salts and for formulation development. Zyntex is a wholesale supplier and distributor of pharmaceutical-grade Paroxetine base, with a CoA and SDS for every lot.

Paroxetine Base Product Overview

Paroxetine base (C19H20FNO3) is the (3S,4R)-enantiomer of the free amine. It is an oily to waxy material or solid that is practically insoluble in water. In medicines, paroxetine is almost always used as a salt.

API producers use the base to make salts such as Paroxetine Hydrochloride and paroxetine mesylate (CAS 217797-14-3), which have better stability and handling properties. Formulation scientists also use it in development work, for example for transdermal and other non-standard dosage forms, and analytical laboratories use it as a reference material.

Zyntex supplies paroxetine base only to licensed pharmaceutical companies and laboratories. Related SSRIs in our range include Sertraline Hydrochloride and Fluoxetine Hydrochloride.

Key Applications of Paroxetine Base

Main application areas:

🧪 Salt Formation

Starting material for paroxetine hydrochloride and mesylate.

🔬 Formulation Development

Base form for non-standard dosage forms.

🧪 Analytical Use

Reference material for testing.

💊 Pharmaceutical Synthesis

Intermediate in API production.

Paroxetine Base Technical Specifications

ParameterStandard Value
Product NameParoxetine (Free Base)
CAS Number61869-08-7
Molecular Formula / WeightC19H20FNO3 / 329.37 g/mol
Purity GradePharmaceutical Grade (API)
DocumentsCoA and SDS with every lot

⚠️ Safety & Handling: Pharmacologically active substance; harmful if swallowed, may damage the unborn child and is very toxic to aquatic life. Avoid contact with skin and eyes; wear gloves and eye protection, and prevent release to the environment. Store in tightly closed containers in a cool place. Always consult the Safety Data Sheet (SDS) for full classification and handling instructions.

Frequently Asked Questions

What is the difference between paroxetine base and paroxetine hydrochloride?

The base is the free amine, used mainly to make salts and for development work. The hydrochloride is the salt used in most tablets.

Who can purchase paroxetine base?

It is supplied only to licensed pharmaceutical companies and laboratories.

How can I get a price and documents?

Prices depend on quantity, packaging and destination. Contact us with your required volume to receive a quotation together with the CoA and SDS.