Miconazole Nitrate
Miconazole Nitrate is a potent imidazole antifungal agent used in pharmaceutical research to study the inhibition of 14α-demethylase and the disruption of fungal cell membrane integrity.
Description
Comprehensive Product Overview
In the field of mycological pharmacology, the ability to selectively inhibit fungal cytochrome P450 enzymes is a major advantage. Miconazole Nitrate is specifically selected because it inhibits the enzyme 14α-demethylase. For instance, it is used to investigate the suppression of Candida and Trichophyton species. Consequently, it facilitates the development of high-efficacy topical and mucosal antifungal formulations with higher efficiency. As a result, Zyntex ensures that our high-purity API is produced under strict quality control to maintain its crystalline stability and ensure optimal bioavailability in lipid-based vehicles.
Moreover, the research-grade Miconazole Nitrate provided by Zyntex is a vital component in the study of intracellular reactive oxygen species (ROS) accumulation in fungal cells. This application allows for the creation of advanced profiles for fungicidal synergy, undoubtedly pushing the boundaries of what is possible in modern anti-infective therapy. At the same time, its secondary antibacterial properties against certain Gram-positive cocci are highly valued by global biotechnology firms. In short, our product serves as a dependable “precision-antifungal” for companies focusing on both skin health and sustainable healthcare infrastructure.
Recently, scientific interest has surged regarding the use of Miconazole in combination with other azoles to bypass drug resistance. Because of this, Zyntex offers specialized analytical documentation to provide safer and more convenient validation in various laboratory environments. Ultimately, by choosing Zyntex as your supplier, you secure a reliable supply chain that balances chemical potency with rigorous logistical safety. To conclude, our commitment to chemical excellence ensures that your manufacturing processes—whether in fine chemistry or clinical research—achieve the highest levels of purity and yield.
Key Industrial Applications
This high-performance antifungal agent is specifically vital in the following four sectors:
🔬 Mycology R&D
A potent agent for studying 14α-demethylase inhibition; thus enabling the production of high-value fungal growth data.
💊 Pharma Development
Key API for creams, ointments, and vaginal suppositories; consequently vital for developing stable topical medications.
🧬 Synergistic Studies
Used to investigate drug combinations for resistant strains; undoubtedly essential for identifying new antifungal pathways.
🧪 Analytical Chemistry
Used as a reference standard in HPLC-based purity assays; specifically helping researchers monitor API concentration in formulations.
Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Miconazole Nitrate |
| Assay / Purity | 99.0% – 101.0% (HPLC) |
| Molecular Formula | C18H14Cl4N2O · HNO3 |
| CAS Number | 22832-87-7 |
⚠️ Safety Warning: Miconazole Nitrate is a potent antifungal agent. Therefore, it must be handled under professional laboratory supervision using appropriate PPE. Avoid inhalation of dust. Store in a cool, dry, and dark environment to prevent chemical degradation and maintain its salt form stability.
Safety and Regulatory Data
For comprehensive toxicological profiles, material safety data sheets (MSDS), and physical property validation, please refer to the official PubChem entry: Chemical Safety Data – Miconazole Nitrate (22832-87-7)
