
Pharmaceutical-grade Levodropropizine (CAS 99291-25-5), 99–101%, min. 99.5% S-isomer, supplied wholesale by Zyntex to licensed producers. Peripheral antitussive API for syrups, drops, tablets and granules. CoA and SDS.
Levodropropizine (C13H20N2O2) is a white or almost white crystalline powder that melts at about 60–63°C. It is the (S)-enantiomer of dropropizine, so chiral purity of at least 99.5% S-isomer is a key specification.
In addition, pharmaceutical companies use it in syrups, oral drops, tablets and granules for dry cough in several European, Asian and Latin American countries. Unlike centrally acting cough suppressants, it acts mainly on sensory nerves in the airways. Similarly, other respiratory APIs in our range include Ambroxol hydrochloride and Bromhexine Hydrochloride.
Because its melting point is low, it requires cool storage. Zyntex supplies levodropropizine only to licensed pharmaceutical companies.
Typical uses include, for example:
🥄 Syrups
API for pediatric as well as adult syrups.
💧 Oral Drops
API for oral drops.
💊 Tablets and Granules
API for solid oral forms.
🔬 Generic Development
Development as well as reference material.
| Parameter | Standard Value |
|---|---|
| Product Name | Levodropropizine (S-Dropropizine) |
| CAS Number | 99291-25-5 |
| Assay / Purity (HPLC) | 99.0% to 101.0% (Dry Basis) |
| Appearance | White or almost white crystalline powder |
| Melting Point | 60°C to 63°C |
| Enantiomeric Purity | Min 99.5% S-isomer (Chiral HPLC) |
| Documents | CoA as well as SDS with every lot |
⚠️ Safety & Handling: Pharmacologically active substance; harmful if swallowed. Avoid inhalation of dust and contact with skin and eyes, and also wear gloves, eye protection and dust protection. Store in tightly closed containers below 25°C, because of its low melting point. Always consult the Safety Data Sheet (SDS), because it contains the full classification and handling instructions.
How does levodropropizine differ from other cough suppressants?
It acts mainly on sensory nerves in the airways, whereas centrally acting cough suppressants act in the brain.
Why is enantiomeric purity important?
Because it is the single (S)-enantiomer, specifications limit the other isomer to ensure consistent quality.
How can I get a price and documents?
Prices depend on quantity, packaging and destination, so please contact us with your required volume. We then send a quotation together with the CoA and SDS.