Hydroxychloroquine Sulfate

Hydroxychloroquine Sulfate is a 4-aminoquinoline derivative used in pharmaceutical research to study the inhibition of autophagy and the management of systemic lupus erythematosus and rheumatoid arthritis.

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Description
Hydroxychloroquine Sulfate is, furthermore, a premier pharmaceutical-grade antimalarial and immunomodulatory reagent supplied by Zyntex for the medical research, rheumatology, and drug development sectors. This white or almost white crystalline powder (CAS 747-36-4) is distinguished by its classification as a lysosomotropic agent. In addition, it possesses a hydroxyl group that differentiates its pharmacokinetic profile from chloroquine, offering reduced ocular toxicity. Therefore, it is extensively utilized as a primary reagent for the study of toll-like receptor (TLR) signaling and as a high-potential material for next-generation autoimmune therapy research.

Comprehensive Product Overview

In the field of molecular immunology and parasitology, the ability to increase lysosomal pH is a major advantage. Hydroxychloroquine Sulfate is specifically selected because it interferes with antigen processing and the glycosylation of proteins. For instance, it is used to investigate the suppression of cytokine storms and the prevention of viral entry via endosomal pathways. Consequently, it facilitates the development of high-efficacy oral DMARD (Disease-Modifying Antirheumatic Drug) formulations with higher efficiency. As a result, Zyntex ensures that our high-purity API is manufactured under strict quality controls to ensure consistent solubility and crystalline stability.

Moreover, the research-grade Hydroxychloroquine Sulfate provided by Zyntex is a vital component in the study of autophagy inhibition in oncology. This application allows for the creation of advanced sensitization profiles for chemotherapy, undoubtedly pushing the boundaries of what is possible in modern cancer research. At the same time, its role in reducing the activation of dendritic cells is highly valued by global clinical research organizations. In short, our product serves as a dependable “precision-immunomodulator” for companies focusing on both chronic inflammation and sustainable healthcare infrastructure.

Recently, scientific interest has surged regarding the use of Hydroxychloroquine in combination with zinc ionophores to study intracellular mineral transport. Because of this, Zyntex offers specialized analytical documentation to provide safer and more convenient validation in various laboratory environments. Ultimately, by choosing Zyntex as your supplier, you secure a reliable supply chain that balances chemical potency with rigorous logistical safety. To conclude, our commitment to chemical excellence ensures that your manufacturing processes—whether in fine chemistry or clinical research—achieve the highest levels of purity and yield.

Key Industrial Applications

This high-performance aminoquinoline is specifically vital in the following four sectors:

🔬 Rheumatology R&D

A potent agent for studying TLR-9 inhibition; thus enabling the production of high-value autoimmune response data.

💊 Pharma Development

Key API for chronic lupus and RA medications; consequently vital for developing stable long-term oral therapies.

🧬 Autophagy Research

Used to block lysosomal degradation; undoubtedly essential for identifying new pathways in protein-misfolding diseases.

🧪 Parasitological Assays

Used to study heme polymerase inhibition; specifically helping researchers compare efficacy against other quinolines.

Technical Specifications

ParameterStandard Value
Product NameHydroxychloroquine Sulfate
Assay / Purity99.0% – 101.0% (Dried Basis)
Molecular FormulaC18H26ClN3O · H2SO4
CAS Number747-36-4

⚠️ Safety Warning: Hydroxychloroquine Sulfate is a potent bioactive compound with cumulative toxicity risks. Therefore, it must be handled under strict laboratory protocols by trained personnel. Store in a cool, dry place and protect from light to prevent potential photochemical degradation of the quinoline ring.

Safety and Regulatory Data

For comprehensive toxicological profiles, material safety data sheets (MSDS), and physical property validation, please refer to the official PubChem entry: Chemical Safety Data – Hydroxychloroquine Sulfate (747-36-4)