Artesunate
Artesunate by Zyntex is a high-purity, water-soluble hemisuccinate derivative of dihydroartemisinin (CAS 88495-63-0). It is recognized by the World Health Organization (WHO) as the first-line treatment for severe malaria, offering rapid parasite clearance and superior clinical outcomes compared to traditional cinchona alkaloids.
Description
Comprehensive Product Overview of Artesunate
Exceptional solubility and rapid parasite reduction provide a major advantage in treating complicated malaria cases. Artesunate works by targeting the ring stage of the parasite cycle, making it a “gold standard” in the manufacturing of emergency antimalarial protocols. It helps clinical teams significantly reduce mortality rates in patients with cerebral malaria. For instance, it is the primary component in producing sterile powder for injection, which is reconstituted at the bedside. Consequently, it enhances the speed of recovery in intensive care units. As a result, Zyntex ensures ultra-low moisture content and strictly controlled pH levels for our supply. This ensures maximum stability and safety in your manufacturing cycles.
Moreover, Zyntex supplies high-grade Artesunate for the development of modern Artemisinin-based Combination Therapies (ACTs). This compound acts as a critical agent in preventing the spread of drug-resistant *Plasmodium* strains. It pushes the boundaries of global health by offering a highly tolerable alternative to older treatments like Quinine. At the same time, it serves as a vital active in research exploring the compound’s potential antiviral and anti-cancer properties. In short, our product serves as a dependable “acute clinical intervention.” It supports both the urgent needs of tropical medicine and the long-term innovation goals of pharmaceutical laboratories.
Recently, scientific interest in Artesunate for its high efficacy in treating non-malarial parasitic infections and certain solid tumors has grown. It provides a versatile platform for drug-repurposing studies. Because of this, Zyntex offers specialized pharmaceutical-grade batches with verified chemical profiles to meet WHO and international pharmacopeia standards. These formats suit modern freeze-drying (lyophilization) technology and specialized tablet coating. Ultimately, choosing Zyntex secures a reliable and transparent pharmaceutical supply chain. We balance complex organic synthesis expertise with rigorous batch-to-batch HPLC and mass spectrometry monitoring. To conclude, our commitment ensures your manufacturing processes achieve the highest levels of performance and stability.
Key Industrial Applications for Artesunate
This essential water-soluble antimalarial is vital in these four sectors:
💉 Hospital-Grade Injectables
Primary API for IV/IM treatments for severe malaria. Thus, it is a critical resource for emergency medicine worldwide.
💊 ACT Tablet Production
Used in oral combination therapies to clear parasites. Consequently, it is vital for standard malaria outpatient regimens.
🔬 Oncology Research
Active ingredient in studies targeting cancer cell apoptosis. Undoubtedly, it is essential for advanced medicinal chemistry.
🌍 Global Health Programs
Bulk API for international aid and epidemic response. Specifically, it supports large-scale humanitarian health efforts.
Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Artesunate |
| Molecular Formula | $C_{19}H_{28}O_{8}$ |
| Purity (HPLC) | ≥ 99.0% |
| CAS Number | 88495-63-0 |
⚠️ Safety & Handling: Artesunate is a potent API. Therefore, it should be handled in a controlled environment using appropriate PPE (nitrile gloves, lab coat, mask). It is hydrolytically unstable in aqueous solution; dry powder must be kept in tightly sealed containers. Store in a cool, dry place (2-8°C recommended for long-term stability) and protect from light to ensure the integrity of the peroxide bridge.
