2-Methyltetrahydrofuran
2-Methyltetrahydrofuran (2-MeTHF, CAS 96-47-9), min. 99.5%, supplied wholesale by Zyntex. Bio-based ether solvent replacing THF and dichloromethane in Grignard reactions, couplings and extractions. CoA and SDS.
Description
2-Methyltetrahydrofuran Product Overview
2-Methyltetrahydrofuran (C5H10O) is a clear, colorless liquid that boils at about 80°C and has a density of about 0.85 g/cm³. Unlike THF, it has limited water solubility (about 14 g per 100 g at room temperature), so it separates cleanly from water. Producers can make it from renewable raw materials such as furfural from agricultural residues.
In addition, pharmaceutical and fine chemical producers use 2-MeTHF for Grignard and organolithium reactions, metal-catalyzed couplings and biphasic reactions. Because the solvent separates from water, workup and solvent recovery become simpler. It also replaces dichloromethane in many extractions, which helps companies reduce chlorinated solvents.
Like other ethers, 2-MeTHF can form peroxides, so commercial grades contain a stabilizer such as BHT, and unstabilized anhydrous grades are available for sensitive chemistry. Related solvents in our range include 1,4-Dioxane, Gamma-Valerolactone (GVL) and MTBE (Methyl Tert-Butyl Ether).
Key Applications of 2-Methyltetrahydrofuran
Typical uses include, for example:
💊 Pharmaceutical Synthesis
Solvent for Grignard and organolithium chemistry.
🔁 Biphasic Reactions
Clean separation from water.
🧪 Extractions
Replacement for dichloromethane.
🌱 Green Chemistry
Bio-based solvent option.
2-Methyltetrahydrofuran Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | 2-Methyltetrahydrofuran (2-MeTHF) |
| CAS Number | 96-47-9 |
| Molecular Formula / Weight | C5H10O / 86.13 g/mol |
| Purity (GC) | Min. 99.5% |
| Boiling Point | Approx. 80 °C |
| Stabilizer | BHT-stabilized or unstabilized grades |
| Documents | CoA and SDS with every lot |
⚠️ Safety & Handling: Highly flammable liquid and vapor that causes serious eye irritation and may form explosive peroxides. Keep away from ignition sources, test for peroxides before distillation, and also wear gloves and eye protection. Store in tightly closed, grounded containers in a cool, ventilated place. Always consult the Safety Data Sheet (SDS), because it contains the full classification and handling instructions.
Frequently Asked Questions
Why is 2-MeTHF considered greener than THF?
It can be made from renewable raw materials, and because it separates from water, solvent recovery is easier.
What is the boiling point of 2-methyltetrahydrofuran?
About 80°C, which is higher than THF and allows reactions at higher temperatures.
How can I get a price and documents?
Prices depend on quantity, packaging and destination, so please contact us with your required volume. We then send a quotation together with the CoA and SDS.
