Voriconazole
Voriconazole (CAS 137234-62-9) is a second-generation triazole antifungal medication used to treat a variety of serious, invasive fungal infections by inhibiting ergosterol biosynthesis.
Description
Comprehensive Product Overview
In the competitive landscape of infectious disease management, the breadth of the antifungal spectrum defines the final outcome. Zyntex Voriconazole is selected for its exceptional efficacy against a wide array of pathogens, including Aspergillus species and fluconazole-resistant Candida. Therefore, we provide a high-purity crystalline powder that acts as a robust inhibitor of fungal cytochrome P450-mediated 14 alpha-lanosterol demethylation. Consequently, this versatile ingredient delivers reliable performance across a wide range of clinical settings, ensuring the successful treatment of invasive aspergillosis and scedosporiosis in immunocompromised patients.
Zyntex supplies Voriconazole in a clean, white to off-white powder form, optimized for easy integration into complex pharmaceutical manufacturing, including intravenous infusions and oral tablets. Our stringent quality control measures ensure a precise enantiomeric profile and excellent stability against environmental degradation. Furthermore, this product features superior tissue distribution, particularly in the central nervous system, making it an ideal candidate for treating fungal meningitis. Since it is effective at achieving high serum concentrations quickly, you can incorporate it into various “intensive therapy” protocols without affecting the safety profile or the dissolution rate of the final dosage form.
From specialized clinical research to large-scale pharmaceutical production, this versatile second-generation triazole is a staple for modern medicine. Its consistent chemical profile ensures it functions effectively as a primary defense against emerging fungal threats. As a result, Zyntex provides a dependable foundation for innovation in the “immunology” and “infectious disease” markets. Finally, our commitment to chemical quality helps your brand achieve international pharmaceutical regulatory and safety standards effortlessly.
Key Industrial Applications
This professional-grade antifungal API is widely utilized in the following sectors:
🏥 Critical Care Medicine
The first-line treatment for invasive aspergillosis in hospitalized and immunocompromised patients.
🎗️ Hematology & Oncology
Essential for prophylactic and empirical antifungal therapy in patients undergoing chemotherapy or bone marrow transplants.
👁️ Ophthalmology
Used in the formulation of specialized eye drops or injections for fungal keratitis and endophthalmitis.
🧪 Pharmacological R&D
Utilized as a reference standard in antifungal susceptibility testing and drug-interaction studies.
Technical Specifications
| Parameter | Specification Standard |
|---|---|
| Product Name | Voriconazole |
| Assay (HPLC) | 98.0% – 102.0% |
| Physical Appearance | White to Off-White Crystalline Powder |
| Specific Rotation | -58° to -62° |
| CAS Number | 137234-62-9 |
🔬 Scientific Data: For detailed molecular structure, metabolic pathway studies, and toxicity profiles, consult: PubChem Entry: Voriconazole (External Link)
