Valproic acid

Zyntex provides high-purity Valproic Acid, a cornerstone anticonvulsant and mood stabilizer. It is essential for managing various seizure types and manic episodes associated with bipolar disorder through its multi-channel inhibitory mechanism.

SKU: 51-52-5 Category: Tag:
Description
Valproic Acid is a foundational broad-spectrum antiepileptic agent supplied by Zyntex. Unlike many narrow-spectrum anticonvulsants, its unique fatty acid structure allows it to treat a wide variety of seizure types. We offer this material (CAS 99-66-1) in Pharmaceutical Grade, ensuring the strict chemical purity required for long-term maintenance therapies in both neurology and psychiatry.

Comprehensive Product Overview

In the global pharmaceutical landscape, Valproic Acid is distinguished by its complex, multi-modal mechanism of action. First, it increases the concentration of gamma-aminobutyric acid (GABA) in the brain by inhibiting GABA transaminase and stimulating GABA synthesis. Second, it blocks voltage-gated sodium channels and T-type calcium channels. As a result, it provides an exceptionally high level of neuronal stabilization, making it effective for absence, myoclonic, and tonic-clonic seizures. Zyntex provides Valproic Acid as a high-purity liquid API, which is the essential precursor for both soft-gel capsules and the synthesis of various salt forms like Sodium Valproate.

Zyntex also supplies Valproic Acid for its critical role in behavioral health. It is a gold-standard treatment for the manic episodes associated with bipolar disorder and is frequently used in migraine prophylaxis. Because Valproic Acid has a specific metabolic pathway involving glucuronidation and mitochondrial beta-oxidation, the consistency of the API is paramount to avoiding hepatotoxic impurities. Moreover, its ability to act as a histone deacetylase (HDAC) inhibitor has opened new avenues in epigenetics and oncology research. Consequently, our product helps manufacturers develop reliable, life-changing medications for patients with refractory neurological and psychiatric conditions. Finally, our comprehensive quality control data and stability profiles ensure seamless integration into your production and regulatory pipelines.

Key Pharmaceutical Applications

This versatile neurological API is a cornerstone in the following therapeutic areas:

🧠 Epilepsy Control

A first-line therapy for generalized and partial seizures, particularly effective in pediatric absence epilepsy.

⚖️ Bipolar Disorder

Widely utilized as a mood stabilizer to treat acute manic or mixed episodes and prevent future relapses.

🤕 Migraine Prophylaxis

Prescribed for the prevention of chronic migraine headaches by reducing neuronal hyperexcitability.

🔬 HDAC Inhibition Research

A key tool in oncology and genetic research for studying gene expression and cell differentiation pathways.

Technical Specifications

ParameterSpecification Standard
Product NameValproic Acid
CAS Number99-66-1
Molecular FormulaC8H16O2
Assay (GC)98.0% – 102.0%
AppearanceColorless to pale yellow, slightly viscous liquid

🔬 Scientific Data: For detailed pharmacokinetics and drug interaction profiles, consult: PubChem Entry: Valproic Acid (External Link)