Tetramisole hydrochloride

Tetramisole Hydrochloride is a racemic mixture of levamisole and dexamisole. Researchers utilize this API as a broad-spectrum anthelmintic and a potent inhibitor of alkaline phosphatases in biochemical assays.

SKU: 5086-74-8 Category: Tags: ,
Description
Tetramisole Hydrochloride (dl-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole HCl) is, furthermore, a premier chemical reagent supplied by Zyntex for the veterinary, life sciences, and biochemical research sectors. This white to pale cream crystalline solid (CAS 5086-74-8) is distinguished by having a dual-action profile as both a nicotinic acetylcholine receptor agonist and a biological response modifier. In addition, it possesses an exceptionally high efficacy against various nematode species. Therefore, it is extensively utilized as a primary reagent for the study of neuromuscular paralysis in parasites and as a specialized inhibitor of non-specific alkaline phosphatase.

Comprehensive Product Overview

In the field of parasitology and enzymology, the ability to selectively disrupt physiological processes is a major advantage. Tetramisole Hydrochloride is specifically selected because it causes rapid neuromuscular depolarization in parasitic worms, leading to spastic paralysis. For instance, it is more stable in aqueous solutions than many other imidazothiazole derivatives. Consequently, it facilitates the study of helminth resistance mechanisms and cellular signaling with higher efficiency. As a result, Zyntex ensures that our high-purity Tetramisole HCl is manufactured to prevent enantiomeric degradation and ensure consistent inhibitory constants ($Ki$) in enzymatic assays.

Moreover, the research-grade Tetramisole Hydrochloride provided by Zyntex is a vital component in the development of staining protocols for immunohistochemistry. This application allows for the reduction of background noise by inhibiting endogenous alkaline phosphatase activity, undoubtedly pushing the boundaries of what is possible in histological imaging and protein detection. At the same time, its role as an immunomodulator that enhances T-cell mediated responses is highly valued by global pharmaceutical firms. In short, our product serves as a dependable “precision-reagent” for companies focusing on both animal health and advanced molecular diagnostics.

Recently, scientific interest has surged regarding the use of $LiBH_4$ and Tetramisole in synergistic formulations for vaccine adjuvant research. Because of this, Zyntex offers high-assay crystalline formats to provide safer and more convenient handling in laboratory environments. Ultimately, by choosing Zyntex as your supplier, you secure a reliable supply chain that balances chemical potency with rigorous logistical safety. To conclude, our commitment to chemical excellence ensures that your manufacturing processes—whether in veterinary pharmacology or diagnostic research—achieve the highest levels of purity and chemical yield.

Key Industrial Applications

This high-potency anthelmintic agent is specifically vital in the following four sectors:

🐾 Veterinary Medicine

A potent reagent for helminth control; thus enabling the production of treatments for livestock and companion animals.

🔬 Enzymology Research

Potent inhibitor of alkaline phosphatase; consequently vital for reducing background signaling in molecular assays.

🧠 Immunology Studies

Investigated as a biological response modifier; undoubtedly essential for studying T-lymphocyte restoration and function.

🧪 Histology & Imaging

Used in staining protocols; specifically helping to control enzymatic reactions during tissue visualization.

Technical Specifications

ParameterStandard Value
Product NameTetramisole Hydrochloride
Assay / PurityMin. 99.0%
Molecular FormulaC11H12N2S · HCl
CAS Number5086-74-8

🔬 Scientific Note: Tetramisole HCl is sensitive to light. Therefore, it must be stored in well-closed, light-resistant containers to maintain its chemical and biological integrity.