Sulfadoxine

Zyntex provides premium Sulfadoxine. This long-acting sulfonamide is a key API for malaria therapy and the treatment of respiratory and urinary tract infections in both humans and livestock.

SKU: 2447-57-6 Category: Tag:
Description
Sulfadoxine is a potent, long-acting sulfonamide antibacterial and antiprotozoal agent supplied by Zyntex. Recognized for its exceptionally long half-life, it is a cornerstone API in the global fight against malaria. We offer this material (CAS 2447-57-6) in Pharmaceutical and Veterinary Grades to ensure consistent therapeutic performance in both human health and large-scale livestock management.

Comprehensive Product Overview

In the landscape of antimicrobial therapy, Sulfadoxine is distinguished by its sustained duration of action. Like other sulfa drugs, it inhibits bacterial and protozoal growth by interfering with the synthesis of dihydrofolic acid. Specifically, it competes with para-aminobenzoic acid (PABA) for the enzyme dihydropteroate synthase. Because of its slow excretion rate, it remains active in the body for an extended period, making it ideal for prophylactic treatments and intermittent preventive therapies. Zyntex provides Sulfadoxine with high chemical stability, ensuring it remains effective even in challenging environmental conditions.

Zyntex also specializes in supplying Sulfadoxine for synergistic drug combinations. When paired with pyrimethamine, it creates a powerful sequential blockade of the folic acid pathway, which is highly effective against Plasmodium falciparum malaria. In addition to its anti-malarial use, it is a vital component in veterinary medicine for treating respiratory, urinary, and gastrointestinal infections in cattle, swine, and poultry. Our API is produced under strict quality control measures to meet international pharmacopeia standards, guaranteeing high bioavailability and minimal impurity levels. Consequently, our product supports manufacturers in developing life-saving medications with reliable dosing intervals. Finally, our logistical expertise ensures that your supply chain remains robust and efficient.

Key Pharmaceutical & Veterinary Applications

This long-acting antimicrobial API is essential for the following specialized sectors:

🦟 Malaria Therapy

A critical component in SP (Sulfadoxine-Pyrimethamine) tablets used for the prevention and treatment of resistant malaria strains.

🐄 Veterinary Infectious Diseases

Applied in livestock to treat foot rot, bacterial pneumonia, and acute metritis due to its broad-spectrum activity.

🏥 Prophylactic Protocols

Used in public health programs for intermittent preventive treatment in pregnant women (IPTp) and infants (IPTi).

🧪 Combination API R&D

Serves as a stable foundation for developing novel fixed-dose combinations targeting multi-drug resistant pathogens.

Technical Specifications

ParameterSpecification Standard
Product NameSulfadoxine
CAS Number2447-57-6
Molecular FormulaC12H14N4O4S
Assay (Purity)Min. 99.0%

🔬 Scientific Data: For detailed pharmacokinetics and metabolic pathway information, consult: PubChem Entry: Sulfadoxine (External Link)