Prilocaine
Pharmaceutical-grade Prilocaine base (CAS 721-50-6), 99–101%, supplied wholesale by Zyntex to licensed producers. Amide local anesthetic API for lidocaine–prilocaine eutectic creams, patches and dental cartridges. CoA and SDS.
Description
Prilocaine Product Overview
Prilocaine base (C13H20N2O) is a white crystalline powder with a low melting point of about 37°C. When producers mix it with Lidocaine Hydrochloride-derived lidocaine base, the two form a eutectic oil at room temperature, which allows high concentrations of anesthetic in a cream.
Pharmaceutical companies use this lidocaine–prilocaine eutectic in creams and patches that numb the skin before needle procedures. Similarly, dental product producers use prilocaine hydrochloride (CAS 1786-81-8) in injectable cartridges, often with felypressin. Other amide local anesthetics in our range also include Bupivacaine Hydrochloride and Ropivacaine Hydrochloride.
Because it can cause methemoglobinemia at high doses, dosing in products carefully remains limited. Zyntex supplies it only to licensed pharmaceutical companies.
Key Applications of Prilocaine
Typical uses include, for example:
🧴 Topical Creams
Eutectic cream with lidocaine.
🩹 Patches
Anesthetic patches for skin.
🦷 Dental Cartridges
Hydrochloride salt for dental injections.
🔬 Generic Development
Development as well as reference material.
Prilocaine Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Prilocaine (Base) |
| CAS Number | 721-50-6 (HCl: 1786-81-8) |
| Molecular Formula / Weight | C13H20N2O / 220.31 g/mol |
| Assay / Purity | 99.0% – 101.0% (HPLC) |
| Melting Point | approx. 37°C |
| Documents | CoA as well as SDS with every lot |
⚠️ Safety & Handling: Pharmacologically active substance; harmful if swallowed and may cause methemoglobinemia at high exposure. Avoid contact and inhalation, and also wear gloves, eye protection and dust protection. Store in tightly closed containers below 25°C, because of its low melting point. Always consult the Safety Data Sheet (SDS), because it contains the full classification and handling instructions.
Frequently Asked Questions
What is a eutectic mixture of lidocaine and prilocaine?
When the two bases are mixed, they melt into an oil at room temperature, so a cream can contain high anesthetic concentrations.
Do you supply the hydrochloride?
Yes. Besides the base for creams, the hydrochloride for dental injections is also available.
How can I get a price and documents?
Prices depend on quantity, packaging and destination, so please contact us with your required volume. We then send a quotation together with the CoA and SDS.
