Phenylephrine Hydrochloride
Phenylephrine Hydrochloride is a premium-grade, white or almost white crystalline adrenerjik receptor powder carrying CAS number 61-76-7. Processed under strict pharmaceutical compliance, this high-purity sympathetic agonist exhibits exceptional vasoconstrictor blocking profiles and complete water solubility, making it an ideal core choice for manufacturing clinical oral tablets, cold relief syrups, and specialized ophthalmic solutions globally.
Description
Adrenergic Agonism Mechanics and Liquid Dose Stability
Excellent crystalline dissolution behavior and outstanding vascular tissue permeability profiles provide a distinct operational edge when engineering modern fast-acting sinus relief formulations. This active pharmaceutical solid operates by selectively stimulating alpha-1 adrenerjik pathways, supplying the exact biological mechanisms required to constrict localized dilated blood vessels without altering raw binder uniformity. It assists compounding engineers in maintaining strict dosage uniformity across high-speed liquid syrup blending runs, mitigating precipitation or layer separation risks within automated volumetric filling lines. For instance, specialized pharmaceutical facilities incorporate this hydrochloride salt as a core active component in multi-symptom cold relief tablet lines. As a consequence, it maximizes the technical throughput of automated compression machinery and continuous quality assurance checks. Consequently, Zyntex coordinates clean room crystallization paths to eliminate downstream polymorph shifts from your factory schedule.
In addition to this, Zyntex coordinates climate-controlled logistics for pilot-scale trials and advanced respiratory formulation research centers. The compound maintains its refined crystalline integrity under strict storage parameters, preventing moisture-induced degradation or chemical breakdown during automated mechanical blending steps. It advances contemporary medical engineering by providing a thoroughly analyzed, highly predictable vasoconstrictor raw material that meets international monograph standards. Simultaneously, it remains a critical chemical standard for routine high-performance liquid chromatography (HPLC) calibrations and bioanalytical validation testing assays. In brief, our product functions as a dependable chemical foundation, supporting both the performance of commercial capsule batches and the analytical rigor of specialized industrial laboratories.
Primary Medical Sectors for Phenylephrine HCl
This high-purity crystalline active drug compound delivers crucial technical value within these four primary industrial sectors:
💊 Nasal Deconjestans
Primary active pharmaceutical source used for formulating uniform, clinical-grade oral anti-cold tablets and sinus capsules. Hence, it directly supports optimal dosage control lines.
🧪 Ophthalmic Drops
Utilized as a high-purity active base to compound rapid-acting pupil-dilating eye drops and specialized vascular drops. Clearly, it is key for uniform dissolving patterns.
🔬 Chromatographic Assays
Acts as an essential reference active standard for adrenergic system receptor binding metrics, assay calibration, and routine laboratory diagnostics. Resultantly, it guarantees excellent matrix clarity.
🏢 Respiratory Research
Used as a professional active component for validating advanced blood-tissue barrier models and specialized liposomal drug carriers. Specifically, it confirms optimal reaction pathways.
Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Phenylephrine Hydrochloride |
| Assay / Purity (HPLC) | Min 98.5% to 101.0% (Dry Basis) |
| Appearance | White or almost white crystalline powder |
| Melting Point | Approx. 143 – 145 °C |
| Solubility | Freely soluble in water and alcohol; practically insoluble in chloroform |
| CAS Number | 61-76-7 |
📝 Safety & Handling: Phenylephrine Hydrochloride is a potent cardiovascular and sympathetic drug API. Inhalation of powder dust or accidental eye/skin contact can trigger temporary blood pressure adjustments, cardiac rate variations, and respiratory tract mucosal irritation. Therefore, store strictly inside original airtight containers within a well-ventilated, dry warehouse zone protected from light, moisture, and elevated temperatures. Prevent airborne powder generation during dispensing loops. Proper protective equipment (PPE)—including nitrile chemical gloves, safety glasses, and a certified dust respirator mask—must be worn during all handling phases. Review the Safety Data Sheet (SDS).
