Glibenclamide
Pharmaceutical-grade Glibenclamide (glyburide, CAS 10238-21-8), 98–102%, supplied wholesale by Zyntex to licensed producers. Sulfonylurea API for antidiabetic tablets and metformin combinations, standard and micronized. CoA and SDS.
Description
Glibenclamide Product Overview
Glibenclamide (C23H28ClN3O5S), known as glyburide in the United States, is a white crystalline powder that is practically insoluble in water. Its low solubility makes particle size important for dissolution, so producers offer standard and micronized grades. It is described in the USP, EP and BP.
Pharmaceutical companies use it in tablets for type 2 diabetes, both alone and in fixed-dose combinations with Metformin Hydrochloride. It belongs to the sulfonylurea class together with Gliclazide and Glimepiride, which differ in dosing and formulation requirements.
Zyntex supplies it from qualified API producers with lot-specific documentation, only to companies licensed for pharmaceutical use in their country.
Key Applications of Glibenclamide
Main application areas:
💊 Oral Tablets
API for sulfonylurea antidiabetic tablets.
🔗 Combination Products
Fixed-dose combinations with metformin.
⚙️ Micronized Formulations
Micronized grades for improved dissolution.
🔬 Generic Development
Development and reference material.
Glibenclamide Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Glibenclamide |
| CAS Number | 10238-21-8 |
| Molecular Formula / Weight | C23H28ClN3O5S / 494.00 g/mol |
| Assay / Purity | Min 98.0% – 102.0% (Pharma Grade) |
| Appearance | White crystalline powder |
| Stability | Stable under standard storage conditions |
| Documents | CoA and SDS with every lot |
⚠️ Safety & Handling: Pharmacologically active substance: avoid inhalation of dust and contact with skin and eyes. Handle in well-ventilated areas with gloves, eye protection and dust protection. Store in tightly closed containers in a cool, dry place. Always consult the Safety Data Sheet (SDS) for full classification and handling instructions.
Frequently Asked Questions
Is glibenclamide the same as glyburide?
Yes. Glibenclamide is the international name and glyburide the name used in the United States for the same API.
Do you supply a micronized grade?
Micronized grades can be quoted on request. Please specify your particle size distribution requirements.
How can I get a price and documents?
Prices depend on quantity, packaging and destination. Contact us with your required volume to receive a quotation together with the CoA and SDS.
