Fosfomycin sodium
Fosfomycin Sodium is a broad-spectrum antibiotic that inhibits the first stage of bacterial cell wall synthesis. Researchers utilize this API to study the inactivation of the MurA enzyme and its efficacy against resistant Gram-negative pathogens.
Description
Comprehensive Product Overview
In the evolving field of antibiotic development, the early-stage inhibition of peptidoglycan formation defines the success of therapy against resistant strains. Specifically, Fosfomycin Sodium functions by covalently binding to the cysteine residue of the enzyme UDP-N-acetylglucosamine enolpyruvyl transferase (MurA). Additionally, researchers select this molecule to study its unique ability to enter bacterial cells via the glycerophosphate ($glpT$) and glucose-6-phosphate ($uhpT$) transport systems. Therefore, whether you investigate carbapenem-resistant Enterobacteriaceae (CRE) or biofilm disruption, this API delivers reliable pharmacological support across various laboratory conditions.
Zyntex maintains a transparent production chain to ensure a precise impurity profile for every batch, focusing on the limitation of related substances and residual solvents. Moreover, our quality control team verifies every lot for pH stability and water content to ensure the integrity of parenteral and lyophilized formulations. For instance, we optimize the crystalline structure to support the development of intravenous dosages used in critical care research. As a result, your lab receives a high-purity reagent for advanced studies into drug-drug synergy and the prevention of bacterial adhesion to uroepithelial cells.
Modern clinical science relies on high-quality phosphonic acid antibiotics to address the gap in treatment for multidrug-resistant Gram-positive and Gram-negative organisms. Because Fosfomycin possesses a documented ability to reduce the nephrotoxicity induced by other agents like aminoglycosides, it remains a primary focus for studies involving combination therapy optimization. Ultimately, Zyntex provides a dependable foundation for your next innovation in antimicrobial stewardship and specialized pharmaceutical engineering.
Specialized Antimicrobial Applications
This high-potency cell wall inhibitor is vital for the following research and production sectors:
🧬 Cell Wall Synthesis Research
Scientists use Fosfomycin to investigate the irreversible blockade of MurA, preventing the conversion of UDP-GlcNAc to UDP-MurNAc.
🦠 MDR Pathogen Studies
Researchers include this API in protocols focused on the susceptibility of ESBL-producing and vancomycin-resistant pathogens.
🧪 Synergistic Modeling
Biotechnicians utilize this molecule to study the enhanced entry of other antibiotics when the cell wall is weakened by Fosfomycin.
💊 Injectable Formulation
This compound serves as a core reactant for engineering stable, high-concentration sodium salts for intravenous clinical research.
Technical Specifications
| Parameter | Specification Standard |
|---|---|
| Product Name | Fosfomycin Sodium (CAS 26016-99-9) |
| Molecular Formula | C3H5Na2O4P |
| Purity | USP / BP Grade (Min. 98%) |
| Appearance | White or almost white crystalline powder |
| Solubility | Very soluble in Water; practically insoluble in Ethanol |
🔬 Scientific Data: For detailed antimicrobial spectra, transport mechanisms, and chemical profiling, consult: PubChem Entry: Fosfomycin Sodium (External Link)
