Doxycycline
Doxycycline API (base / monohydrate, CAS 564-25-0) supplied wholesale by Zyntex to licensed pharmaceutical and veterinary producers. Tetracycline-class API for capsules, tablets and oral suspensions. CoA and SDS with every lot.
Description
Doxycycline Product Overview
Doxycycline (C22H24N2O8) is a semi-synthetic tetracycline. The base is mostly supplied as the monohydrate (CAS 17086-28-1), a yellow crystalline powder that is very slightly soluble in water. Because it is less soluble and less acidic than the salt form, formulators choose it for capsules, tablets and oral suspensions where a milder taste and lower acidity matter.
The other common form is Doxycycline Hyclate, the hydrochloride salt, which dissolves much better in water and suits injectables and soluble products. Both forms belong to the tetracycline family together with Tetracycline, Oxytetracycline and Minocycline hydrochloride.
Pharmaceutical and veterinary companies use it in oral formulations for humans and animals. Zyntex supplies it from qualified API producers, with lot-specific documentation, only to companies licensed for pharmaceutical or veterinary use in their country.
Key Applications of Doxycycline
Main application areas:
💊 Oral Solid Forms
API for capsules and tablets.
🥄 Oral Suspensions
Base form preferred for suspensions with milder taste.
🐾 Veterinary Medicines
API for veterinary oral products.
🔬 Generic Development
Reference and development material for generic dossiers.
Doxycycline Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Doxycycline (Base / Monohydrate) |
| CAS Number | 564-25-0 (monohydrate: 17086-28-1) |
| Molecular Formula / Weight | C22H24N2O8·H2O / 462.45 g/mol (monohydrate) |
| Appearance | Yellow crystalline powder |
| Assay / Purity | Per USP/EP, stated on lot CoA |
| Solubility | Very slightly soluble in water |
| Documents | CoA and SDS with every lot |
⚠️ Safety & Handling: Pharmacologically active substance that may damage the unborn child and may cause allergic reactions. Avoid inhalation of dust and contact with skin and eyes; wear gloves, eye protection and dust protection. Store in tightly closed, light-resistant containers in a cool, dry place. Always consult the Safety Data Sheet (SDS) for full classification and handling instructions.
Frequently Asked Questions
What is the difference between the base and the hyclate?
The base (monohydrate) is poorly water-soluble and used in capsules, tablets and suspensions. The hyclate is the hydrochloride salt, highly water-soluble and suited to injectables and soluble products.
Who can purchase this API?
It is supplied to pharmaceutical and veterinary companies that hold the licenses required for API purchase and use in their country.
How can I get a price and documents?
Prices depend on quantity, packaging and destination. Contact us with your required volume to receive a quotation together with the CoA and SDS.
