
Pharmaceutical-grade Betamethasone (CAS 378-44-9), 97–103%, supplied wholesale by Zyntex to licensed producers. Potent fluorinated corticosteroid API for tablets, oral solutions and injectables. CoA and SDS with every lot.
Betamethasone (C22H29FO5) is a white to creamy white crystalline powder that is practically insoluble in water. It is a fluorinated glucocorticoid and a stereoisomer of Dexamethasone, differing only in the orientation of one methyl group.
Pharmaceutical companies use the free alcohol in tablets, oral solutions and some injectables. For skin products, they mainly use its esters, such as the valerate and dipropionate esters, which penetrate the skin better. Other corticosteroid APIs in our range include Prednisolone and Hydrocortisone.
As a highly potent steroid, it requires contained handling during production. Zyntex supplies it from qualified API producers, only to licensed pharmaceutical companies.
Main application areas:
💊 Tablets
API for oral corticosteroid tablets.
🥄 Oral Solutions
API for oral liquid formulations.
💉 Injectables
API for injectable preparations.
🧪 Ester Synthesis
Parent compound for topical esters.
| Parameter | Standard Value |
|---|---|
| Product Name | Betamethasone |
| CAS Number | 378-44-9 |
| Molecular Formula / Weight | C22H29FO5 / 392.46 g/mol |
| Appearance | White to creamy white crystalline powder |
| Assay / Purity | 97.0% – 103.0% (Pharma Grade) |
| Documents | CoA and SDS with every lot |
⚠️ Safety & Handling: Highly potent corticosteroid that may damage fertility or the unborn child and cause organ damage through prolonged exposure. Handle in contained systems with suitable respiratory protection, gloves and protective clothing. Store in tightly closed, light-resistant containers in a cool, dry place. Always consult the Safety Data Sheet (SDS) for full classification and handling instructions.
What is the difference between the free alcohol and its esters?
The free alcohol is used in tablets and some injectables, while esters such as valerate and dipropionate are used in creams and ointments because they penetrate the skin better.
Who can purchase this API?
It is supplied only to pharmaceutical companies holding the licenses required for API purchase and use in their country.
How can I get a price and documents?
Prices depend on quantity, packaging and destination. Contact us with your required volume to receive a quotation together with the CoA and SDS.