Amoxicillin + Potassium Clavulanate
Pharmaceutical-grade Amoxicillin + Potassium Clavulanate blends (co-amoxiclav, CAS 74469-00-4) in 2:1 to 8:1 ratios, supplied wholesale by Zyntex to licensed producers. For tablets, suspensions and veterinary products. CoA and SDS.
Description
Amoxicillin + Potassium Clavulanate Product Overview
The product combines amoxicillin, usually as the trihydrate (CAS 61336-70-7), with potassium clavulanate (CAS 61177-45-5) in defined ratios such as 2:1, 4:1, 7:1 or 8:1. Using a pre-blended API saves formulators a difficult blending step, because clavulanate is extremely sensitive to moisture.
Pharmaceutical companies use these blends in film-coated tablets, chewable tablets and powders for oral suspension; for injection, sodium salts are combined in sterile form. The single components are also available as Amoxicillin 3-hydrate and Clavulanate Potassium. Veterinary producers use the combination in tablets and injectables for companion animals.
Production must take place under very low humidity and in dedicated beta-lactam facilities. Zyntex supplies these blends only to licensed pharmaceutical and veterinary companies. For a related penicillin–inhibitor combination, see Piperacillin Tazobactam.
Key Applications of Amoxicillin + Potassium Clavulanate
Main application areas:
💊 Tablets
Pre-blended API for film-coated and chewable tablets.
🥄 Oral Suspensions
API blend for pediatric powders for suspension.
🐕 Veterinary Products
API for companion animal tablets and injectables.
🔬 Generic Development
Development material in defined ratios.
Amoxicillin + Potassium Clavulanate Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Amoxicillin + Potassium Clavulanate |
| CAS Registry Number | 74469-00-4 (trihydrate component: 61336-70-7; clavulanate potassium: 61177-45-5) |
| Ratios | 2:1, 4:1, 7:1 or 8:1 (amoxicillin : clavulanic acid) |
| Material Grade | Pharmaceutical Grade |
| Documents | CoA and SDS with every lot |
⚠️ Safety & Handling: Beta-lactam antibiotics that may cause allergic skin and respiratory reactions. Handle in dedicated facilities under low humidity with gloves, eye protection and respiratory protection. Store sealed in a cool, dry place, because clavulanate degrades rapidly with moisture. Always consult the Safety Data Sheet (SDS) for full classification and handling instructions.
Frequently Asked Questions
Which ratios are available?
Common ratios are 2:1, 4:1, 7:1 and 8:1 amoxicillin to clavulanic acid. Please state your ratio and dosage form when requesting a quote.
Why use a pre-blended API?
Clavulanate is very moisture-sensitive, and pre-blended material reduces handling and blending steps in the formulator’s plant.
How can I get a price and documents?
Prices depend on quantity, packaging and destination. Contact us with your required volume to receive a quotation together with the CoA and SDS.
