Amodiaquine hydrochloride
Amodiaquine hydrochloride by Zyntex is a potent 4-aminoquinoline antimalarial agent (C20H22ClN3O⋅2HCl⋅2H2O). It is a vital Active Pharmaceutical Ingredient (API) used primarily in the formulation of oral medications to treat acute malaria attacks and as a key component in Artemisinin-based Combination Therapy (ACT).
Description
Comprehensive Product Overview
Exceptional schizonticidal activity and a rapid onset of action provide a major advantage in acute malaria management. Amodiaquine hydrochloride works as a core component in the manufacturing of frontline antimalarial drugs, particularly in regions where malaria is endemic. It helps achieve rapid clinical improvement and parasite clearance in patients. For instance, it is a primary component in producing co-blistered or fixed-dose combinations with artesunate. Consequently, it enhances the efficacy of modern treatment protocols and helps delay the development of drug resistance. As a result, Zyntex ensures precise purity levels and rigorous moisture content control for our supply. This ensures maximum therapeutic performance and predictable shelf-life in your manufacturing cycles.
Moreover, Zyntex supplies high-grade Amodiaquine for the pharmaceutical research and public health sectors. This compound acts as a critical benchmark for studying the mechanisms of quinoline-based drug resistance in protozoal pathogens. It pushes the boundaries of parasitology by providing a reliable tool for enzymatic and molecular studies. At the same time, it serves as a reliable reference material in pharmacokinetic and bio-analytical laboratories. In short, our product serves as a dependable “active pharmaceutical ingredient.” It supports both the rigorous requirements of commercial drug production and the innovation of infectious disease research.
Recently, scientific interest in Amodiaquine for its potential applications in seasonal malaria chemoprevention (SMC) has grown. It provides a stable chemical profile for developing long-acting formulations that protect vulnerable populations during high-transmission seasons. Because of this, Zyntex offers specialized batches with verified chemical profiles to meet international pharmacopoeia (USP/BP/EP) standards. These formats suit modern pharmaceutical engineering and large-scale public health programs. Ultimately, choosing Zyntex secures a reliable and transparent chemical supply chain. We balance synthesis expertise with rigorous batch-to-batch quality monitoring. To conclude, our commitment ensures your manufacturing processes achieve the highest levels of performance and clinical efficacy.
Key Industrial Applications
This high-performance API is vital in these four sectors:
💊 Pharma Manufacturing
Primary raw material for tablets and oral liquids. Thus, it is a staple in the production of essential antimalarial medicines.
🌍 Public Health Programs
Key API for large-scale chemoprevention initiatives. Consequently, it is vital for reducing malaria morbidity in endemic regions.
🔬 Parasitology Research
Used for studying parasite metabolism and drug resistance mechanisms. Undoubtedly, it supports the discovery of new therapies.
🧪 Clinical Trials
Active component in evaluating new combination therapies. Specifically, it facilitates the development of next-generation ACTs.
Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Amodiaquine hydrochloride |
| Molecular Formula | $C_{20}H_{22}ClN_{3}O cdot 2HCl cdot 2H_{2}O$ |
| Assay (Dried Basis) | 98.0% – 102.0% |
| CAS Number | 6398-98-7 |
⚠️ Safety Note: Amodiaquine hydrochloride can cause hepatic injury or blood dyscrasias if used long-term for prophylaxis. Therefore, handle with appropriate personal protective equipment (PPE) and maintain strict compliance with pharmaceutical manufacturing safety protocols.
