Terlipressin
Terlipressin (Zyntex) is a synthetic triglycyl-lysine-vasopressin analogue used primarily for the treatment of bleeding esophageal varices and hepatorenal syndrome.
Description
Terlipressin Product Overview
Maximum hemodynamic stability provides a major advantage in intensive care units. Terlipressin effectively controls bleeding from esophageal varices by inducing splanchnic vasoconstriction. This feature makes it a cornerstone therapy in hepatology for improving survival rates during acute bleeding episodes. For instance, it is the only vasoactive drug proven to improve survival in patients with Type 1 hepatorenal syndrome (HRS). Consequently, it supports improved renal function by increasing arterial pressure and renal perfusion. As a result, Zyntex produces Terlipressin with exceptional chemical purity, ensuring total potency in sterile lyophilized powders and injectable solutions.
Moreover, Zyntex provides pharmaceutical-grade peptides for advanced research in septic shock and refractory hypotension. This application allows for the study of non-catecholamine vasopressors in hemodynamically unstable patients. It pushes the boundaries of modern resuscitation science. At the same time, healthcare formulators value its role in developing user-friendly pre-filled syringes for rapid clinical response. In short, our product serves as a dependable “portal hypotensive agent.” It supports both hospital supply chains and specialized hepatology research globally. Recently, interest in Terlipressin for managing surgical complications in liver transplants has grown, highlighting its expanding clinical utility.
Terlipressin Key Applications
This high-potency synthetic peptide is vital in these four specialized sectors:
🏥 Emergency Hepatology
It is the primary active for variceal bleeding. Thus, it provides immediate control of portal hypertension during crises.
🩺 Hepatorenal Syndrome
It serves as a key agent for reversing acute renal failure. Consequently, it helps restore kidney function in cirrhotic patients.
🧪 Critical Care R&D
It works as a tool for studying catecholamine-resistant shock. Undoubtedly, it is essential for advanced hemodynamic research.
🔬 Pharma Injection Mfg
It acts as a primary active for sterile APIs. Specifically, it aids in formulating stable, high-purity hospital medications.
Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Terlipressin |
| Purity (HPLC) | ≥ 98.5% |
| Molecular Formula | C52H74N16O15S2 |
| CAS Number | 14636-12-5 |
⚠️ Usage Note: Terlipressin should be used with extreme caution in patients with coronary artery disease or peripheral vascular disease due to its potent vasoconstrictive effects. Therefore, continuous hemodynamic monitoring is mandatory. Store under refrigeration ($2°C$ to $8°C$) to ensure peptide integrity.
