Sildenafil Citrate
Sildenafil Citrate is a potent and selective phosphodiesterase-5 (PDE5) inhibitor used in pharmaceutical research to study the modulation of cGMP-mediated vasodilation and pulmonary arterial hypertension.
Description
Comprehensive Product Overview
In the field of vascular biology and sexual medicine, the ability to increase cyclic guanosine monophosphate (cGMP) levels is a major advantage. Sildenafil Citrate is specifically selected because of its high selectivity for the PDE5 enzyme found predominantly in the corpus cavernosum and pulmonary vasculature. For instance, it is used to investigate the physiological management of erectile dysfunction and pulmonary arterial hypertension (PAH). Consequently, it facilitates the development of high-efficacy oral tablets and oral disintegrating films with higher efficiency. As a result, Zyntex ensures that our high-purity API maintains strict crystalline uniformity and meets global pharmacopoeial standards for solubility and heavy metal limits.
Moreover, the research-grade Sildenafil Citrate provided by Zyntex is a vital component in the study of nitric oxide signaling pathways in non-urological tissues. This application allows for the creation of advanced profiles for cardioprotective research, undoubtedly pushing the boundaries of what is possible in modern cardiovascular therapy. At the same time, its role in improving exercise capacity in PAH patients is highly valued by global pharmaceutical research organizations. In short, our product serves as a dependable “precision-inhibitor” for companies focusing on both men’s health and specialized vascular care infrastructure.
Recently, scientific interest has surged regarding the use of Sildenafil in neuroprotective research and its impact on cerebral blood flow. Because of this, Zyntex offers specialized analytical documentation to provide safer and more convenient validation in various laboratory environments. Ultimately, by choosing Zyntex as your supplier, you secure a reliable supply chain that balances chemical potency with rigorous logistical safety. To conclude, our commitment to chemical excellence ensures that your manufacturing processes—whether in fine chemistry or clinical research—achieve the highest levels of purity and yield.
Key Industrial Applications
This high-performance enzyme inhibitor is specifically vital in the following four sectors:
🔬 Urology R&D
A potent agent for studying erectile physiology; thus enabling the production of high-value hemodynamic data.
💊 Pharma Development
Key API for first-line ED and PAH medications; consequently vital for developing stable clinical formulations.
🧪 Cardiopulmonary Studies
Used to investigate pulmonary vasodilation; undoubtedly essential for identifying new hypertension treatments.
🧬 cGMP Signaling
Used to map cyclic nucleotide pathways; specifically helping researchers study intracellular messenger regulation.
Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Sildenafil Citrate |
| Assay / Purity | 98.0% – 102.0% (HPLC) |
| Molecular Formula | C22H30N6O4S · C6H8O7 |
| CAS Number | 171599-03-0 |
⚠️ Safety Warning: Sildenafil Citrate is a potent vasodilator. Therefore, it must not be handled by individuals with severe cardiovascular conditions or those using nitrate medications. It should be managed by trained laboratory professionals with appropriate PPE. Store in a cool, dry place and protect from light to prevent chemical degradation of the citrate salt.
Safety and Regulatory Data
For comprehensive toxicological profiles, material safety data sheets (MSDS), and physical property validation, please refer to the official PubChem entry: Chemical Safety Data – Sildenafil Citrate (171599-03-0)
